Latest Wellness Trend: Trans-Geranylgeraniol Supplementation Boosts Testosterone in Hashimoto’s—A Case Study
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|A new case report published by LaGrutta A et al in "Alternative Therapies in Health and Medicine" explores a natural, integrative approach to testosterone optimization for men with Hashimoto's thyroiditis. The study chronicles the experience of a 27-year-old male struggling with thyroid autoimmunity, hormone imbalance, and gut dysbiosis—and reveals promising benefits from targeted trans-geranylgeraniol supplementation.
What Was the Study’s Aim?
The case report aimed to evaluate the impact of a systems-based, non-pharmacological intervention—particularly trans-geranylgeraniol supplementation—on testosterone levels and overall health in a patient with Hashimoto’s thyroiditis and declining androgen status.
How Was the Study Conducted?
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The patient’s care began with foundational lifestyle modifications:
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An anti-inflammatory diet removing gluten and dairy.
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Correction of vitamin D deficiency with D3/K2 supplementation.
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Gut support using digestive enzymes and increased intake of polyphenol-rich foods.
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Thyroid biomarkers improved over time with these holistic interventions.
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In 2023, the patient’s testosterone began to decline, affecting muscle mass and athletic performance.
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To directly address this, he received 600mg/day trans-geranylgeraniol (Annatto-GG™ 300) for nine weeks.
What Were the Results?
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Testosterone levels increased significantly after nine weeks of trans-geranylgeraniol supplementation.
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The patient noticed clear improvements in muscle strength and physical performance.
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Lab tests and clinical outcomes suggested enhanced endocrine and immune system balance.
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The approach also supported metabolic resilience and gut-thyroid axis health, underscoring the interplay between nutrition, hormones, and immune function.
What’s the Takeaway?
This case demonstrates that a comprehensive, integrative strategy—including targeted trans-geranylgeraniol supplementation—can naturally and effectively improve testosterone levels in men with Hashimoto’s. The findings advocate for a multifaceted, non-pharmacological framework, emphasizing the value of supporting gut health, micronutrient status, and endocrine function to address complex autoimmune and hormonal challenges.
Read the full case report:
PubMed – Boosting Testosterone Naturally in Hashimoto's
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